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omicverse

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@omicverse

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97Public Repos
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72Published Skills

Building interoperable open-source tools for next-generation omics data analysis.

Skills Distribution
DomainData Systems...Single-Cell Genomics (40%)Spatial Transcript.. (25%)Bulk RNA-Seq Analy.. (20%)Microbiome & Metab.. (15%)

Agent Skills by omicverse

Showing 72 vetted skills indexed across 3 GitHub repositories.

omicverseomicverse
13

omicverse-reference-label-transfer

Transfer cell-type labels from reference to query AnnData objects.

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Advanced
omicverseomicverse
13

omicverse-bulk-celltype-deconvolution

Infer cell-type fractions from bulk RNA-seq using a paired single-cell reference.

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Advanced
omicverseomicverse
13

omicverse-single-cell-cellrank-fate

Maps RNA velocity to CellRank terminal-state probabilities for AnnData workflows.

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omicverseomicverse
13

omicverse-single-cell-cellvote-consensus

Build consensus cell-type labels for AnnData objects with conflicting single-cell annotations.

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omicverseomicverse
13

omicverse-single-cell-cellphonedb-communication

Analyze single-cell ligand-receptor communication from annotated AnnData objects.

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Advanced
omicverseomicverse
13

omicverse-microbiome-da-comparison

Compare microbiome differential-abundance results across Wilcoxon, pyDESeq2, and ANCOM-BC on AnnData cohorts.

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Advanced
omicverseomicverse
13

omicverse-single-cell-monocle2-trajectory

Fit Monocle2-style trajectories on AnnData to derive pseudotime and branch-dependent gene programs.

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Advanced
omicverseomicverse
13

omicverse-single-cell-liana-communication

Infer ligand-receptor communication from annotated single-cell AnnData objects.

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Advanced
omicverseomicverse
13

omicverse-single-cell-scenic

Convert single-cell SCENIC analysis into a reusable regulon workflow for AnnData datasets.

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omicverseomicverse
13

omicverse-single-cell-cnmf-program-discovery

Discover gene programs in single-cell AnnData datasets with OmicVerse cNMF.

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omicverseomicverse
13

omicverse-single-cell-cellmatch-ontology

Map free-text cell-type labels to canonical Cell Ontology terms.

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omicverseomicverse
13

omicverse-cross-modal-celltype-transfer

Transfer cell-type labels between AnnData objects using weighted KNN mapping.

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Intermediate
omicverseomicverse
13

omicverse-single-cell-cytotrace2

Predict single-cell developmental potency from AnnData with OmicVerse CytoTRACE2.

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omicverseomicverse
13

omicverse-bulk-metabol-untargeted-lipidomics

Analyze untargeted LC-MS metabolomics and lipidomics data in AnnData.

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omicverseomicverse
13

omicverse-single-cell-preprocessing

Convert OmicVerse single-cell AnnData objects into cluster-ready preprocessing and marker-discovery workflows.

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omicverseomicverse
13

omicverse-microbiome-16s-amplicon-dada2

Builds 16S amplicon analysis from FASTQs to AnnData with taxonomy and diversity.

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omicverseomicverse
13

omicverse-microbiome-phylogeny

Build phylogenetic trees and compute tree-aware diversity metrics from 16S amplicon data.

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omicverseomicverse
13

omicverse-micro-metabol-paired

Detect microbe-metabolite associations across matched samples using Spearman correlation, CCA, and MMvec workflows.

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omicverseomicverse
13

omicverse-single-cell-annotation

Annotate clustered AnnData objects with OmicVerse cell-type labels.

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omicverseomicverse
13

omicverse-single-cell-batch-integration

Run OmicVerse single-cell batch integration on preprocessed AnnData objects.

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omicverseomicverse
13

omicverse-single-cell-metatime-annotation

Annotate tumor single-cell AnnData objects with MetaTiME cell-state labels.

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omicverseomicverse
13

omicverse-bulk-metabol-preprocessing

Preprocess metabolomics peak tables into analysis-ready AnnData objects.

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omicverseomicverse
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omicverse-bulk-metabol-multivariate

Discriminate two metabolomics groups and select biomarkers from preprocessed AnnData.

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omicverseomicverse
13

omicverse-single-cell-differential-expression

Run single-cell differential expression analysis on AnnData datasets with Wilcoxon, t-test, or memento-de workflows.

Official
Advanced

Frequently Asked Questions About omicverse

FAQPage Schema
What specific biological data analysis tasks does Omicverse support?▼

Omicverse enables end-to-end processing of single-cell RNA-seq, spatial transcriptomics, bulk RNA-seq, and microbiome data. It supports tasks including cell-type annotation, trajectory inference, ligand-receptor communication mapping, differential expression analysis, and multi-omics data integration using standardized AnnData objects.

Who is the target user for these computational analysis methods?▼

The target users are bioinformaticians, computational biologists, and genomics researchers who require standardized, interoperable methods for processing high-dimensional biological datasets. It is designed for researchers performing secondary and tertiary analysis on sequencing data generated from platforms like 10x Genomics or LC-MS.

What are the primary dependencies for running these analysis methods?▼

Omicverse relies on the AnnData ecosystem and integrates with standard libraries such as Scanpy, SciPy, and StatsModels. Users must have a local environment capable of handling large-scale matrix operations and should be familiar with standard bioinformatics file formats like h5ad, gmt, and fastq.